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مجله پژوهش در بهداشت محیط

مجله پژوهش در بهداشت محیط

ارزیابی پارامتر های تنفسی کارکنان در مواجهه با ترکیبات BTEX در یک شرکت پالایش نفت

نوع مقاله : مقالات پژوهشی

نویسندگان
صمد جلیلیان 1
سیما سبزعلیپور 2
مریم محمدی روزبهانی 2
لیلا ابراهیمی‌قوام‌آبادی 2
ابراهیم رجب‌زاده‌قطرمی 3
1 دانشجوى دکتراى رشته آلودگى محیط‌زیست، گروه علوم محیط‌زیست، واحد اهواز، دانشگاه آزاداسلامى، اهواز، ایران.
2 استادیار، گروه علوم محیط‌زیست، واحد اهواز، دانشگاه آزاد اسلامى، اهواز، ایران.
3 استادیار، گروه شیلات، دانشکده منابع‌طبیعى دریا، دانشگاه علوم و فنون دریایى خرمشهر، خرمشهر، ایران.
10.22038/jreh.2024.24890
چکیده
زمینه و هدف:  ترکیبات بتیکس از مهمترین آلاینده‌های شیمیایی هوای محیط کار در صنعت نفت هستند که اثرات سوء بهداشتی بر کارکنان این صنعت دارند. این پژوهش با هدف ارزیابی و سنجش غلظت ترکیبات بتیکس و اثرات احتمالی آن‌ها بر پارامترهای تنفسی کارکنان شرکت پالایش نفت آبادان انجام شد. 

مواد و روش‌ها: در این مطالعه 80 کارگر مورد بررسی قرار گرفتند. نمونه‌برداری از ناحیه تنفسی کارکنان مواجهه‌یافته بر اساس روش 1501 سازمان نایوش (NIOSH) با استفاده از پمپ نمونه‌برداری فردی فعال شرکت SKC انگلستان مدل 44-224 MTX  و با استفاده از تیوب‌های جاذب زغال فعال  SKC(مدل 01-226) انجام شد و سنجش پارامترهای تنفسی توسط دستگاه اسپیرومتری میکرولب ساخت کشور ایتالیا از کمپانی MIR انجام شد.

یافته‌ها: نتایج ، نشان دادند که میانگین غلظت ترکیبات تولوئن، اتیل بنزن و زایلن در ناحیه‌ی تنفسی کارکنان مواجهه‌یافته پایین‌تر از حد مجاز استانداردها قرار دارد اما میانگین غلظت ترکیب بنزن بالاتر از حد مجاز قرار دارد. نتایج نشان دادند که تفاوت معنی‌داری بین پارامترهای تنفسی دو گروه کارکنان وجود ندارد و بین میانگین پارامترهای تنفسی FEV1 با FVC در دو گروه کارکنان ارتباط مستقیم و معناداری وجود دارد و هیچ ارتباط معنی‌داری بین پارامترهای تنفسی و مشخصات دموگرافیک در دو گروه را مشاهده نشد. 

نتیجه‌گیری: با توجه به این‌که میانگین غلظت ترکیب بنزن بالاتر از حدمجاز استانداردهای توصیه‌شده قرار دارد، برای کنترل آن نیاز است که از راه کنترل‌های فنی مهندسی و مدیریت، بازرسی‌های دوره‌ای اقدام لازم برای کاهش غلظت و حذف این ترکیب صورت پذیرد. 
کلیدواژه‌ها
بنزن
تولوئن
اتیل بنزن
زایلن
اسپیرومتری
کارکنان

عنوان مقاله English

Evaluation of Respiratory Parameters of Workers Exposed to BTEX Compounds in an Oil Refining Company

نویسندگان English

Samad Jalilian 1
Sima Sabzalipour 2
Maryam Mohammadi Rouzbahani 2
Leila Ibrahimy Ghavamabadi 2
Ebrahim Rajabzadeh Ghatrami 3
1 PhD student in the field of environmental pollution, Department of Environment, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran.
2 Assistant Professor, Department of Environment, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran
3 Assistant Professor, Department of Fisheries, Faculty of Marine Natural Resources. Khorramshahr University of Marine Science and Technology. Khorramshahr. Iran.
چکیده English

Background and Purpose: BTEX compounds are one of the most important chemical air pollutants in the oil industry, which have adverse health effects on the employees of this industry. This research was conducted with the aim of evaluating and measuring the concentration of BTEX compounds and their possible effects on the respiratory parameters of the employees of Abadan Oil Refining Company.

Materials and Methods: In this study, 80 workers were examined. Sampling of the respiratory area of the exposed workers was performed according to the NIOSH method 1501 using an active personal sampling pump of SKC UK company, model 44-224 MTX and using SKC activated carbon absorbent tubes(model 226-01) and the measurement of respiratory parameters was done by a microlab spirometry device made in Italy by MIR company.

Results: The results showed that the average concentration of toluene, ethylbenzene and xylene compounds in the respiratory area of the exposed workers is lower than the standard limit, but the average concentration of benzene compound is above the limit. The results showed that there is no significant difference between the respiratory parameters of the two groups of employees, and there is a direct and significant relationship between the average respiratory parameters of FEV1 and FVC in the two groups of employees, and there is no significant relationship between the respiratory parameters and demographic characteristics in the two groups. It didn't happen.

Conclusion: Considering that the average concentration of benzene compound is higher than the permissible limit of the recommended standards, to control it, it is necessary to take necessary measures to reduce the concentration and remove this compound through technical engineering and management controls, periodic inspections.
 
 
Open Access Policy: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/

کلیدواژه‌ها English

Benzene
Toluene
Ethylbenzene
Xylene
Spirometry
Staff
  1. Keenth W, Cecilf W, Wayent D. Air pollution( Its origin and control). California: Addison Wesley; 2010:5-27.
  2. Linz, DH., de Garmo, PL., Morton, WE., Wiens, AN., Coull, BM. and Maricle, RA.1986, . Organic solvent-induced encephalopathy in industrial painters. J of Occup Med.28,PP, 119-25.
  3. D. Das, V. Gaur and N. Verma, Carbon 42(2004) 2949. https://doi.org/10.1016/j.carbon.2004.07.008
  4. C.L. Chen, H.Y. fang, and M. Shu,(2005) Taiwan J. Air Waste Manage. Assoc. 50(2005) 1487. https://doi.org/10.1080/10473289.2005.10464741 PMid:16295274
  5. B.T. Mohammad, M.C. Veiga, C. Kennes, Biotechnol. Bioeng. 2007.
  6. Chao CY, Chan GY. Quantification of indoor VOCs in twenty mechanically ventilated buildings in Hong Kong. Atmos Environ 2001; 35:5895-.319 https://doi.org/10.1016/S1352-2310(01)00410-1
  7. Jonidi Jafari A KM, Rezaei Kalantary R, Arfaeinia H. Photocatalytic abatement of o-xylene using adsorption enhanced ZnO/GAC catalyst in a continuous flow reactor: Catalytic potential, Fate of o-xylene and its by-. Global NEST J. 2017.
  8. continuous flow reactor: Catalytic potential, Fate of o-xylene and its by-. Global NEST J. 2017.
  9. Bielefeldt AR, Stensel HD. Evaluation of biodegradation kinetic testing methods and longterm variability in biokinetics for BTEX metabolism. Water Research. 1999 Feb. https://doi.org/10.1016/S0043-1354(98)00257-7
  10. Mehdi Jalali, e.a., Health risk assessment of exposure to BETX compounds Jayga gasoline fule distribution chicks Sciences, 2014.(Persian).
  11. (OSHA), O.S.a.H.A., Regulated Hazardous Substances US Department of Labor, 2012.
  12. Bielefeldt AR, Stensel HD. Evaluation of biodegradation kinetic testing methods and longterm variability in biokinetics for BTEX metabolism. Water Research. 1999 Feb. https://doi.org/10.1016/S0043-1354(98)00257-7
  13. Li S, Chen S, Zhu L, Chen X, Yao C, Shen X. Concentrations and risk assessment of selected monoaromatic hydrocarbons in buses and bus stations of Hangzhou, China. Sci Total Environ. 2009;407(6):2004-11. https://doi.org/10.1016/j.scitotenv.2008.11.020 PMid:19101019
  14. Msash H. Assessing Emissions of Volatile Organic Compounds from Landfills Gas. J Health Sci Surveil Sys. 2016;4.
  15. Cranmer, JM. and Goldenberg, M.,1986. Proceedings of theworkshop on neurobehavioral effects of solvents. Neuro Toxicology,7(3) pp,45- 54.
  16. Arlien-Soborg, P., Bruhn, P., Gyldested, C. and Melgaard, B.,1979 Chronic painters' syndrome. Chronic toxic encephalopathy in house painters. Acta Neurol Scand, 60 pp-149-56. https://doi.org/10.1111/j.1600-0404.1979.tb02962.x
  17. Martyn T.S. 2010. Advances in understandingbenzene health effects and susceptibilit . Annual Review of Public Health 31: 133-48. https://doi.org/10.1146/annurev.publhealth.012809.103646 PMid:20070208 PMCid:PMC4360999
  18. Huff, J. 2007. Benzene-induced cancers: abridged history and occupational healt impact. International Journal of Occupational and Environmental Health 13(2): 213-234. https://doi.org/10.1179/oeh.2007.13.2.213 PMid:17718179 PMCid:PMC3363002
  19. Rana, S.V., Y., Verma. 2005. Biochemical toxicity of benzene. Journal of Environmental Biology 26(2): 157-68.
  20. Mosaddegh MH, Tahmasebi N, Barkhordari A, Fallahzadeh H, Soltanizadeh K. The investigation of exposure to BTEX with solid phase Microextraction Method in gas station in Yazd province. Toloue Behdasht 2012;(4): 17-24
  21. Fazlzadeh Davil M, Rostami R, Zarei A, Feizizadeh M, Mahdavi M, Mohammadi A, Eskandari D.A
  22. Survey of 24 Hour Variation of BTEX Concentration in the Ambient Air of Tehran. J Babol Univ Med Sci, 2012;(4): 50-5
  23. Van Vleet, TR. and Schnellmann, RG.,2003 Toxicnephropathy: nvironmental chemicals. Semin Nephrol ,23 pp, 8-500.. https://doi.org/10.1016/S0270-9295(03)00094-9 PMid:13680539
  24. Takigawa, T., Horike, T., Ohashi, Y., Kataoka, H., Wang, DH. and Kira, S.,2004. Were volatile organic compounds the inducing factors for subjective symptoms of employeesworking in newly constructed hospitals? Environ Toxicol,19 pp, 90-280. https://doi.org/10.1002/tox.20035 PMid:15269897
  25. Wong O, Raabe GK. A critical review of cancer epidemiology in the petroleum industry, with a metaanalysis of a combined database of more than 350,000 workers. Regulatory Toxicology and Pharmacology. 2000;32(1):78-98. https://doi.org/10.1006/rtph.2000.1410 PMid:11029272
  26. Cetin E, Odabasi M, Seyfioglu R. Ambient volatile organic compound(VOC) concentrations around a petrochemical complex and a petroleum refinery. Science ofthe Total Environment. 2003;312(1):10312. https://doi.org/10.1016/S0048-9697(03)00197-9 PMid:12873403
  27. Maghsoodi Moghadam R, Bahrami A, Ghorbani F, Mahjub H, Malaki D. Investigation of Qualitative and Quantitative of Volatile Organic Compounds of Ambient Air in the Mahshahr Petrochemical Complex In 2009. Journal of research in health sciences. 2013;13(1):69-74.
  28. Tunsaringkarn, T., Siriwong, W., Rungsiyothin, A., & Nopparatbundit, S.(2012). Occupational exposure of gasoline station workers to BTEX compounds in Bangkok, Thailand, International Journal of Occupational and Environmental Medicine, 3, 3, pp. 117-125.
  29. Rappaport, S. M., Waidyanatha, S., Qu, Q., Shore. R., Jin, X., Cohen, B., Chen, L. C., Melikian, A. A., Li, G., Yin, S., Yan, H., Xu, B., Mu, R., Li, Y., Zhang, X., & Li, K.(2002). Albumin adducts ofbenzene oxide and 1,4-benzoquinone as measures of human benzene metabolism. Cancer Research, 62, 5, pp. 1330-1337
  30. Egeghy, P. P., Hauf-Cabalo, L., Gibson, R., & Rappaport, S. M.(2003). Benzene and naphthalene in air and breath as indicators of exposure to jet fuel, Occupational and environmental medicine, 60, 12, pp. 969-976. https://doi.org/10.1136/oem.60.12.969 PMid:14634191 PMCid:PMC1740428
  31. Thurlbeck, W.M., Churg, A.M.(1995). Pathology of the Lung, Thieme, New York.
  32. Tsai, S. P., Fox, E. E., Ransdell, J. D., Wendt, J. K., Waddell, L. C., & Donnelly, R. P.(2004). A hematology surveillance study of petrochemical workers exposed to benzene, Regulatory Toxicology and Pharmacology, 40, 1, pp. 67-73. https://doi.org/10.1016/j.yrtph.2004.05.010 PMid:15265607
  33. Aurora, P., Stocks, J., Oliver, C., Saunders, C., Castle, R., Chaziparasidis, G., & Bush, A.(2004). Quality control for spirometry in preschool children with and without lung disease, American Journal of Respiratory and Critical Care Medicine, 169, 10, pp. 1152-1159. https://doi.org/10.1164/rccm.200310-1453OC PMid:15028561
  34. 34. National Institute for Occupational Safety and Health(NIOSH)., 2005,. Method 1501, Issue 3.
  35. Karimi et al., validation of high-performance liquid chromatography (HPLC) method to identify and determine the amount of lysinoalanine in infant formula. Iranian Journal of Nutrition Sciences and Food Industries, 2016.11(2) pp. 137-146.(Persian).
  36. Soleymani E. Fundamental of sampling and occupational exposure assessment metod to gases and vapors. 1st ed. Tehran: Fanavarav; 2015,243,248,269,274.(Persian).
  37. Hygiene.AA. EASC-IHSTAT-V235 2014 [Available from: Https://Www.Aiha.Org/GetInvolved/ Volunteergroups/Strategybook4/Appendix IV/EASCIHSTAT-V235.Xls35- Hygiene AA. EASC-IHSTAT-V235-1. 2014. Available At: Https://Www.Aiha.Org/GetInvolved/Volunteergroups/Strategybook4/Appendix IV/EASC-IHSTAT-V235.Xls, 2014.
  38. Zeynali Khadije. Relationship between humoral andinflammatory immune parameters with respiratory indices in young girls in response to increasing exercise activity. [Thesis]. Urmiya: Faculty of Physical Education and Sport Sciences, Urmiya University; 2013. [Farsi]
  39. Nici L, Donner C, Wouters E,Zuwallack R, Ambrosino N, Bourbeau J. An Official American Thoracic Society/European Respiratory Society Statement: Key Concepts and Advances in Pulmonary Rehabilitation. American Journal of Respiratory Cell and Molecular Biology 2006; 173: 1390-1413. https://doi.org/10.1164/rccm.200508-1211ST PMid:16760357
  40. Fani, Mohammad Javad, 2014, investigation of spirometry indicators and pulmonary problems of auto parts manufacturing workers, Tanin Salamat magazine, number 4, third period. .(Persian).
  41. A Semi-Quantitative Method to Assess Occupational Exposuer to Harmful Chemicals MINISTRY OF MANPOWER Occupationl Safety and Health Division.
  42. Giahi, Omid et al., 2013, investigating the relationship between exposure to inhaled pollutants and pulmonary function capacities of workers in a steel industry, scientific journal of Kurdistan University of Medical Sciences / 19th term / winter 2013/145-135. .(Persian).
  43. H KS, FS H, M M. Investigation and evalution of VOC in indoor air and public places.: J, Environ Stud(JES).; 2004.(Persian)
  44. Masekameni, M. D., Moolla, R., Gulumian, M., & Brouwer, D.(2019). Risk assessment of benzene, toluene, ethyl benzene, and xylene concentrations from the combustion of coal in a controlled laboratory environment, International Journal of Environmental Research and Public Health, 16, 1, pp. 95. https://doi.org/10.3390/ijerph16010095 PMid:30602669 PMCid:PMC6339150
  45. Heibati, B., Pollitt, K. J. G., Karimi, A., Charati, J. Y., Ducatman, A., Shokrzadeh, M., & Mohammadyan, M.(2017). BTEX exposure assessment and quantitative risk assessment among petroleum product distributors, Ecotoxicology and environmental safety, 144, pp. 445-449. https://doi.org/10.1016/j.ecoenv.2017.06.055 PMid:28666218
  46. Integrated Risk Information System(IRIS)(2020). Chemical Assessment Summary: Benzene.(cfpub.epa.gov/ncea/iris/iris_documents/documents/subst/0276_summary.pdf(2020/02/26
  47. Abakay, A., Atilgan, S., Abakay, O., Atalay, Y., Guven, S., Yaman, F., ... & Tanrikulu, A. C.(2013). Frequency of respiratory function disorders among dental laboratory technicians working under conditions of high dust concentration, European Review for Medical and Pharmacological Sciences, 17, 6, 809-814.